EKOS therapy is a minimally invasive system for dissolving thrombus. The ultrasonic core generates an acoustic field which greatly accelerates lytic dispersion by driving the drug deeper into the clot and unwinding the fibrin to expose plasminogen receptor sites. 

Acoustic Pulse Thrombolysis™

• Speeds time-to-clot dissolution.
• Results in quality clinical outcomes.
• Increases clot removal and enhances clinical improvement compared to either standard catheter-directed drug therapy or thrombectomy.
• Requires significantly shorter treatment times compared to standard CDT.

Targets the Thrombus Safely

• Lowers the risk of bleeding and other complications.
• Dissolves clots without damaging vessels, valves or walls.

More Effective Drug Delivery

• Reduces dosage requirements by as much as 68% compared to standard, catheter-directed drug therapy.
• Requires up to 4x less drug dosage than traditional systemic delivery.
• Reduces RV/LV ratio with as little as 8mg total tPA used in combination with EKOS therapy.

Superior Clot Clearance

• 48% greater drug absorption within 1 hour.
• 84% greater drug absorption within 2 hours.

The EkoSonic Endovascular System is indicated for the:

• Ultrasound facilitated, controlled and selective infusion of physician-specified fluids, including thrombolytics, into the vasculature for the treatment of pulmonary embolism.
• Infusion of solutions into the pulmonary arteries.
• Controlled and selective infusion of physician-specified fluids, including thrombolytics, into the peripheral vasculature.

All therapeutic agents utilized with the EkoSonic Endovascular System should be fully prepared and used according to the instruction for use of the specific therapeutic agent.

• Not designed for peripheral vasculature dilation purposes.
• This system is contraindicated when, in the medical judgment of the physician, such a procedure may compromise the patient’s condition.

• Vessel perforation or rupture
• Distal embolization of blood clots
• Vessel spasm
• Hemorrhage
• Hematoma
• Pain and tenderness
• Sepsis/Infection
• Thrombophlebitis
• Tricuspid and pulmonic valve damage
• Pulmonary infarct due to tip migration and spontaneous wedging, air embolism, and/or thromboembolism
• Right bundle branch block and complete heart block
• Intimal disruption
• Arterial dissection
• Vascular thrombosis
• Drug reactions
• Allergic reaction to contrast medium
• Arteriovenous fistula
• Thromboembolic episodes
• Amputation
• Pneumothorax
• Perforation of the pulmonary artery.
• Cardiac Arrhythmias – most frequently occurring during placement, removal or following displacement into the right ventricle.